A dangerous and unprecedented heat wave is hitting the West, with temperatures reaching 25-to-40 degrees above normal across the region.
A dozen cities recorded all-time record March temperatures on Wednesday, including 105 degrees in Palm Springs, California; 102 degrees in Phoenix, Arizona; and 94 degrees in Las Vegas.
Heat stroke vs. heat exhaustion: Safety tips as dangerous temperatures hit US
Heat alerts are in place for 40 million Americans in the West through the weekend.
With temperatures expected to reach between 96 and 109 degrees for a widespread area over multiple days -- and during a time of high tourism to the Desert Southwest -- the heat may turn deadly.
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The heat will spread east through the week. By Friday, the record highs may reach Texas, Nebraska and Oklahoma, and by Sunday, daily record highs could stretch from Los Angeles to Memphis, Tennessee.
How to conserve energy during a heat wave
The heat and dry weather could also increase the risk of wildfires. Red flag warnings are in place for parts of Wyoming, South Dakota and Nebraska, where wind gusts could reach 30 to 45 mph.
Extreme heat is considered the deadliest weather-related hazard in the U.S., according to the Fifth National Climate Assessment. About 2,000 Americans die each year on average from extreme heat, according to the Centers for Disease Control and Prevention.
Click herefor what to know about staying safe in the heat.